Thorne Stress Test

At-home collection. Meaningful insights. Personalized plan.

The adrenal glands help us handle stress. This at-home saliva test provides insights about your stress response and adrenal health by measuring hormone fluctuations. Results include a personalized health plan.

You should take this test if you:

Feel tired but wired
Can’t wake up without strong coffee
Crave sugar, especially late in the day
Get sick when you are under stress
Feel irritable, anxious, or depressed
Experience stress often

What You'll Discover

Measures - Your personal biomarker values are displayed on an easy-to-read dashboard with descriptions of what each biomarker value means for you.
Analysis - Using your biomarkers, we provide detailed insights to help identify potential health risks or specific areas of improvement. Insights are generated using Thorne's Health Intelligence platform.
Improvement Plan - Based on your unique results, a comprehensive improvement plan with diet, activity, and supplement recommendations is generated.

What We Measure

Cortisol (4) - Cortisol is the primary stress hormone excreted by the adrenal glands. Cortisol moderates the body’s daily and long-term responses to stress. A healthy cortisol level better regulates energy, mood, focus, and immune response.
DHEA - Dehydroepiandrosterone (DHEA) is the other major hormone excreted by the adrenal glands. DHEA helps to balance cortisol, especially when cortisol’s level gets too high. DHEA is also a precursor to reproductive hormones like estrogen and testosterone.

How It Works

Order and activate

After your purchase is complete, everything you need for your at-home test is delivered to your door. Use the activation code located on the back of the test kit to activate your test on thorne.com and complete your health profile.

Collect samples and send

Referencing the directions booklet included in your test kit, complete your sample collection from the comfort of your home. Use the prepaid shipper to mail your samples directly to the laboratory.

Receive results and recommendations

Your results will be reviewed by an independent, board-certified physician. Once you’ve sent your samples to the lab, after 8-10 business days you will receive your results with meaningful insights and personalized recommendations to promote your health and wellness.

Potential Indicators

Your 24-hour cortisol pattern and your DHEA level determine whether your stress response is healthy. Depending on your results, you could be experiencing some of these symptoms:

Effects of stress on your body include:

Headache
Muscle tension or pain
Chest pain
Fatigue
Change in sex drive
Upset stomach
Sleep problems

Effects of stress on your mood include:

Anxiety
Restlessness
Lack of motivation or focus
Feeling overwhelmed
Irritability or anger
Sadness or depression

Effects of stress on your behavior include:

Overeating or undereating
Angry outbursts
Drug or alcohol abuse
Tobacco use
Social withdrawal
Exercising less often

Stress Test 101

Aspects of Stress

When our adrenal glands function optimally, they produce adequate amounts of cortisol and DHEA to help us cope with stress and power us through the day.

Whether stress comes from our outside environment, like traffic and crowds, or from within, like the anxiety we experience from family or job issues, healthy secretion of cortisol and DHEA from the adrenal glands help us adapt to these situations.

The human stress response is based on two factors ‐ one, the actual stressors (the events and circumstances that impact our life), and two, how we cope with these stressors (how we interpret and respond to them).

Hopefully, we can exert:

Control over the stressors by identifying what circumstances can be changed for the better, although these are often the stressors over which we often have the least control.
Control over the coping response, including behavioral responses and biological responses (interpretation, language, empathy, understanding, medical treatment, diet, nutrition, movement/physical activity, sleep habits). These are the stressors over which we often have the most control.

How the biomarkers we measure impact your health

Testing for the levels of cortisol and DHEA in your body reveals the pattern of these two key measures of our stress response ‐ stressors and coping. The degree to which your cortisol and DHEA levels fall outside the normal range can be used to guide dietary, exercise, lifestyle, and supplement recommendations.

Cortisol and DHEA

Cortisol has wide-ranging effects in the body: it interacts with the reproductive, immune, and endocrine systems. Cortisol, as part of the stress response, prepares the body for a "fight-or-flight" response by suppressing the production and release of other hormones, such as DHEA and thyroid hormones. Normally, cortisol levels have a rhythm of ebbing and flowing during the day, and your cortisol level is highest in the morning and lowest at night. Thorne's Stress Test takes four saliva samples at four time-points during the day to capture your true cortisol rhythm. Stressors, such as those present in your work or home life, often trigger a release of cortisol, either acutely or persistently, and can affect your health in a variety of negative ways.

DHEA, although produced in the adrenal glands, is also produced in smaller amounts in your brain and sex organs. DHEA is a precursor molecule for testosterone and estrogen synthesis, and, thus, it has many other effects in the body. A person's DHEA production generally declines with age.

Metabolically in the body, cortisol and DHEA are antagonistic to each other. The hormones exist in an ever-changing "tug-of-war" with each other, and when one is elevated, the other is usually lower.

Mental Health/Stress Relief

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